What is Methadone?

Methadone is a synthetic opioid which was created after WWII due to a shortage in Morphine. Today it is commonly prescribed to patients suffering from opioid withdrawal and for pain management. After consumption of Methadone the body will metabolize a compound known as EDDP. It is important to know this for when screening a user of Methadone, whether it be to ensure proper use or detect abuse, it remains the most reliable option.

Cut-Off Levels (ng/mL)

200 ng/mL (Urine)

Window of Detection

1 – 3 Days (Urine)

How is it Used?

Methadone can be administered orally in a tablet and by intravenous and intramuscular injection.

What are the Effects?

Abuse of methadone can lead to psychological dependence. When an individual uses methadone, he/she may experience physical symptoms like sweating, itchy skin, or sleepiness. Individuals who abuse methadone risk becoming tolerant of and physically dependent on the drug. When use is stopped a user may suffer from withdrawal symptoms similar to that of other opioids.

Common Symptoms

  • Anxiety
  • Muscle Tremors
  • Nausea
  • Diarrhea
  • Vomiting
  • Abdominal Cramps

Common Street Names

  • Amidone
  • Chocolate Chip Cookies
  • Fizzies
  • Maria
  • Pastora
  • Salvia
  • Street Methadone
  • Wafer

What does it Look Like?

Methadone is available as a tablet, oral solution, or injectable liquid. Tablets are available in 5 mg and 10 mg formulations. As of January 1, 2008, manufacturers of methadone hydrochloride tablets 40 mg (dispersible) have voluntarily agreed to restrict distribution of this formulation to only those facilities authorized for detoxification and maintenance treatment of opioid addiction, and hospitals. Manufacturers will instruct their wholesale distributors to discontinue supplying this formulation to any facility not meeting the above criteria. 

Legal Status

Schedule II substance under the U.S. Controlled Substance Act. Non-Medical use of Methadone is illegal.

Testing Options

  • Integrated Urine Test Cup
  • Urine Test Dip Card
  • Oral Fluid Test
  • Field Test 

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