What is Buprenorphine?

Buprenorphine, combined with naloxone, is in a drug class of opioid partial-agonist antagonist, meaning it has less efficacy, or lesser effects, by the way it binds to the opioid receptors in the brain. Commercially known by the brand Suboxone, Buprenorphine is prescribed to treat people with opioid addiction by a way of weening someone off a much stronger opioid like Heroin or Oxycodone. Buprenorphine can lessen the withdrawal symptoms that come with the stoppage of use with opioids and is often tested to make sure that a patient is taking the prescribe dosage.

Cut-Off Levels (ng/mL)

5, 10 ng/mL (Urine)

5, 10 ng/mL (Saliva)

Window of Detection

1 – 3 Days (Urine)

1 – 2 Days (Saliva)

How is it Used?

Buprenorphine comes in a sublingual tablet and sublingual film to be placed under the tongue and dissolved as well as a buccal film which is place between the cheek and gums.

What are the Effects?

When taken as prescribed Buprenorphine can lessen withdrawal symptoms that are seen in people addicted to opioids when they stop using. If taken in high dosages in can produce similar effects of other much more powerful opioids.

Common Symptoms

  • headache
  • stomach pain
  • constipation
  • difficulty falling asleep or staying asleep
  • mouth numbness or redness
  • tongue pain
  • blurred vision
  • back pain
  • death

Common Street Names

  • Subs
  • Bups
  • Bupies

What does it Look Like?

Small rectangular pieces of film, like a breath strip, usually orange or yellow in color.

Legal Status

Schedule II under the U.S. Controlled Substances Act.

Testing Options

  • Integrated Urine Cup Test
  • Urine Dip Card Test
  • Oral Fluid Test

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