Opiates
OPI
Primary Products
DrugSURE® Integrated Test Cups
DrugSURE® Dip Tests
OralTox® Oral Fluid Tests
What are Opiates?
Opiates are a class of drugs derived directly from the opium poppy plant and include substances such as morphine, codeine, and heroin. They are central nervous system depressants that act on opioid receptors to relieve pain, produce sedation, and create feelings of euphoria. Pharmaceutical opiates (like morphine and codeine) are used medically for pain management, anesthesia support, and cough suppression. These medications typically appear as tablets, capsules, oral syrups, or injectable liquids in regulated clinical settings.
Illicit opiates—particularly heroin—are commonly found as powder (white, tan, or brown), sticky tar-like substances (“black tar heroin”), or compressed forms depending on how they are manufactured. These forms are often snorted, smoked, or injected recreationally to achieve intense euphoria, but they carry significant risks due to unknown purity, adulterants, and high addiction potential. Misuse of pharmaceutical opiates, whether crushed and snorted or injected, also represents a major pathway to opiate dependence.
Effects:
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Pain relief and deep physical relaxation
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Sense of euphoria or “rush” (especially with heroin)
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Slowed breathing and heart rate
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Drowsiness and sedation
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Constricted (“pinpoint”) pupils
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Nausea and vomiting
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Itching or flushed skin
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Impaired coordination and slowed reaction time
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High risk of tolerance, dependence, and addiction
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Potential for respiratory depression leading to overdose
Commons Slang Terms:
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Smack
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H
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Dope
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Junk
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Horse
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Skag
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Dragon
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Down
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M
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Brown sugar
Legal Status:
Opiates are controlled substances under the U.S. Controlled Substances Act, primarily classified as Schedule II (e.g., morphine, codeine) due to their legitimate medical uses and high potential for abuse. Heroin, however, is classified as Schedule I, meaning it has no accepted medical use and is illegal to manufacture, possess, or use. Because both prescribed and illicit opiate use pose safety, impairment, and compliance risks, opiates are a core component of virtually all standard rapid testing panels used in workplaces, treatment centers, courts, and government programs.
In POC toxicology programs, a positive opiate screen requires confirmatory laboratory testing, especially because certain opiates (like codeine) may be legally prescribed. Programs must verify prescriptions when applicable and distinguish between naturally occurring opiates, synthetic opioids, and semi-synthetic opioids depending on the panel used. Due to ongoing opioid misuse and the overdose crisis, opiate screening continues to be a critical element of compliance, risk mitigation, and public safety protocols across regulated and non-regulated testing environments.
Screening Options:
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